Activities of moxifloxacin alone and in combination with other antimicrobial agents against multidrug-resistant Mycobacterium tuberculosis infection in BALB/c mice.

نویسندگان

  • Lanfranco Fattorini
  • Dejiang Tan
  • Elisabetta Iona
  • Maurizio Mattei
  • Federico Giannoni
  • Lara Brunori
  • Simona Recchia
  • Graziella Orefici
چکیده

The activity of moxifloxacin was enhanced by the addition of ethionamide but not by that of cycloserine, thiacetazone, capreomycin, para-aminosalicylic acid, or linezolid in BALB/c mice infected with a strain of Mycobacterium tuberculosis resistant to isoniazid, rifampin, and six other drugs. These observations are important for the therapy of multidrug-resistant tuberculosis.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 47 1  شماره 

صفحات  -

تاریخ انتشار 2003